Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 15/20 | 0.78 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.56 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.54 |
| ▸ | GRN | P28799 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123119 | 0.95 | GPR132 (0.77) | GPR132CMKLR2CMKLR1SMPD1GRN | |
| SCHEMBL1123390 | 0.93 | GPR132 (0.68) | GPR132CMKLR2CMKLR1GRNSORT1 | |
| SCHEMBL1122740 | 0.91 | GPR132 (0.66) | GPR132CMKLR2CMKLR1SMPD1CTSL | |
| SCHEMBL1123259 | 0.87 | GPR132 (0.68) | GPR132CMKLR2CMKLR1SMPD1GRN | |
| SCHEMBL1123253 | 0.87 | GPR132 (0.65) | GPR132CMKLR2CMKLR1SMPD1CTSL | |
| SCHEMBL1123574 | 0.85 | GPR132 (0.58) | GPR132CTSLCTSSCTSBCTSK | |
| SCHEMBL1123575 | 0.85 | GPR132 (0.58) | GPR132CTSLCTSSCTSBCTSK | |
| SCHEMBL18114408 | 0.83 | GPR132 (0.65) | GPR132GRNSORT1CTSLCTSS | |
| SCHEMBL1123379 | 0.83 | GPR132 (0.95) | GPR132CMKLR2CMKLR1SMPD1 | |
| SCHEMBL1122784 | 0.82 | GPR132 (0.62) | GPR132GRNSORT1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |