Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.42 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.41 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 4/20 | 0.41 |
| ▸ | FEN1 | P39748 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460989 | 0.86 | PLOD2 (0.41) | PLOD2PLOD3PLOD1ERCC5FEN1 | |
| SCHEMBL10876692 | 0.77 | GSK3B (0.59) | PLOD2PLOD3PLOD1ERCC5FEN1 | |
| SCHEMBL28407046 | 0.77 | PLOD2 (0.47) | PLOD2PLOD3PLOD1ERCC5FEN1 | |
| SCHEMBL28409166 | 0.76 | PLOD2 (0.46) | PLOD2PLOD3PLOD1ERCC5FEN1 | |
| SCHEMBL5551328 | 0.76 | DAO (0.48) | PLOD2PLOD3PLOD1ERCC5FEN1 | |
| SCHEMBL347869 | 0.76 | GSK3B (0.58) | PLOD2PLOD3PLOD1ERCC5FEN1 | |
| SCHEMBL347813 | 0.72 | PLOD2 (0.42) | PLOD2PLOD3PLOD1ERCC5FEN1 | |
| SCHEMBL5903783 | 0.72 | PLOD2 (0.42) | PLOD2PLOD3PLOD1ERCC5FEN1 | |
| SCHEMBL15851416 | 0.70 | LMNA (0.48) | LMNAPPARGNCOA2NCOA1NPSR1 | |
| SCHEMBL3244368 | 0.70 | HDAC4 (0.68) | PLOD2PLOD3PLOD1ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146236-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORP. (FI) | 2010-12-23 | — | — | WO | disclosed |