Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461014 | 0.86 | CNR1 (0.50) | CNR1ALDH1A1NPSR1CA12CA1 | |
| SCHEMBL3460910 | 0.84 | CNR1 (0.47) | CNR1ALDH1A1NPSR1CA12CA1 | |
| SCHEMBL3459990 | 0.84 | ALDH1A1 (0.48) | CNR1ALDH1A1NPSR1CA12CA1 | |
| SCHEMBL3461493 | 0.83 | MAPT (0.44) | CNR1ALDH1A1NPSR1CA12CA1 | |
| SCHEMBL3462135 | 0.83 | ALDH1A1 (0.47) | CNR1ALDH1A1NPSR1CA12CA1 | |
| SCHEMBL3461544 | 0.81 | ITGB1 (0.60) | CNR1ALDH1A1CA12CA1CA2 | |
| SCHEMBL3460857 | 0.79 | HCRTR2 (0.48) | CNR1ALDH1A1NPSR1CA12CA1 | |
| SCHEMBL3461216 | 0.79 | MGLL (0.47) | CNR1ALDH1A1NPSR1CA12CA1 | |
| SCHEMBL3461746 | 0.75 | ALDH1A1 (0.44) | CNR1ALDH1A1NPSR1CA12CA1 | |
| SCHEMBL7807791 | 0.73 | CNR1 (0.54) | CNR1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146236-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORP. (FI) | 2010-12-23 | — | — | WO | disclosed |