Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.54 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.53 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.53 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461375 | 0.92 | CNR1 (0.54) | CNR1KCNJ6KCNJ5KCNJ3CA2 | |
| SCHEMBL3461544 | 0.87 | ITGB1 (0.60) | CNR1CA2CA9CA12CA1 | |
| SCHEMBL3461085 | 0.85 | CNR1 (0.51) | CNR1CA2CA9CA12CA1 | |
| SCHEMBL7811207 | 0.82 | LMNA (0.55) | CNR1CA2CA9CA12CA1 | |
| SCHEMBL7798880 | 0.80 | MAPT (0.55) | CNR1CA2CA9CA12CA1 | |
| SCHEMBL7805558 | 0.79 | IDH2 (0.61) | CNR1CA2CA9CA12CA1 | |
| SCHEMBL7804129 | 0.78 | PFKFB3 (0.60) | CNR1CA2CA9CA12CA1 | |
| SCHEMBL3468684 | 0.78 | NAMPT (0.56) | CNR1CA2CA9CA12CA1 | |
| SCHEMBL3460910 | 0.77 | CNR1 (0.47) | CNR1CA2CA9CA12CA1 | |
| SCHEMBL11956180 | 0.76 | DDX3X (0.51) | CNR1CA2CA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2012-08-02 | — | — | US | disclosed |
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2012-08-02 | — | — | US | disclosed |
| WO-2010146236-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORP. (FI) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | ITGA1, ITGB1, ITGA2B | CNR1 174/4885KCNJ6 3121/4885KCNJ5 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.