Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158694 | 0.85 | TNFSF11 (0.56) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL2042498 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL30661876 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL2087809 | 0.82 | ALDH1A1 (0.63) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL27468061 | 0.81 | VCP (0.54) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL10019210 | 0.81 | POLB (0.50) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL29082090 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL27512814 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL13041058 | 0.80 | MAPT (0.53) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL15328150 | 0.78 | TNFSF11 (0.51) | ALDH1A1KDM4ECYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833987-A4 | A SINGLE-STEP PLATFORM FOR ON-CHIP INTEGRATION OF BIO-MOLECULES | YEDA RES & DEV (IL) | 2009-03-11 | — | — | EP | claimed |
| EP-1833987-A2 | A SINGLE-STEP PLATFORM FOR ON-CHIP INTEGRATION OF BIO-MOLECULES | Yeda Research and Development Co. Ltd. at The Weizmann Institute of Science (IL) | 2007-09-19 | — | — | EP | claimed |
| WO-2006064505-A2 | A SINGLE-STEP PLATFORM FOR ON-CHIP INTEGRATION OF BIO-MOLECULES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2006-06-22 | — | — | WO | claimed |
| WO-2021150844-A1 | COMPOSITIONS CONTAINING 1,1-DISUBSTITUTED ACTIVATED ALKENES USEFUL IN ADDITIVE MANUFACTURING AND ARTICLES FORMED THEREFROM | SIRRUS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |
| US-8679776-B2 | Activatable dyes | UNIVERSITY OF MASSACHUSETTS (US) | 2014-03-25 | — | — | US | disclosed |
| EP-1833987-B1 | A SINGLE-STEP PLATFORM FOR ON-CHIP INTEGRATION OF BIO-MOLECULES | YEDA RES & DEV (IL) | 2012-08-08 | — | — | EP | disclosed |
| US-20100297684-A1 | ACTIVATIBLE DYES | UNIVERSITY OF MASSACHUSETTS | 2010-11-25 | — | — | US | disclosed |
| US-20100112569-A1 | MICROFLUIDIC DEVICES AND METHODS OF GENERATING AND USING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2010-05-06 | — | — | US | disclosed |
| US-20100056392-A1 | MICROSTRUCTURE AND MICRODOMAIN MICROARRAYS, METHODS OF MAKING SAME AND USES THEREOF | ENERGY, UNITED STATES DEPARTMENT OF | 2010-03-04 | — | — | US | disclosed |
| WO-2009036351-A2 | ACTIVATIBLE DYES | UNIVERSITY OF MASSACHUSETTS (US) | 2009-03-19 | — | — | WO | disclosed |
| EP-1833987-A4 | A SINGLE-STEP PLATFORM FOR ON-CHIP INTEGRATION OF BIO-MOLECULES | YEDA RES & DEV (IL) | 2009-03-11 | — | — | EP | disclosed |
| US-20030235851-A1 | Fusion proteins; combinatorial libraries | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-25 | — | — | US | disclosed |
| WO-2003089454-A2 | UNNATURAL AMINO ACID CONTAINING DISPLAY LIBRARIES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-10-30 | — | — | WO | disclosed |
| US-5556961-A | Nucleosides with 5'-O-photolabile protecting groups | AFFYMETRIX, INC. | 1996-09-17 | — | — | US | disclosed |
| US-5482867-A | Spatially-addressable immobilization of anti-ligands on surfaces | AFFYMAX TECHNOLOGIES N.V. (NL) | 1996-01-09 | — | — | US | disclosed |
| US-5451683-A | Spatially-addressable immobilization of anti-ligands on surfaces | AFFYMAX TECHNOLOGIES N.V. | 1995-09-19 | — | — | US | disclosed |
| US-5252743-A | Using cage binding compound | AFFYMAX TECHNOLOGIES N.V. (NL) | 1993-10-12 | — | — | US | disclosed |
| EP-0502060-A4 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0502060-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991007087-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1991-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297684-A1 | ACTIVATIBLE DYES | IK, MB, HMBS | ALDH1A1 856/4885KDM4E 3095/4885CYP3A4 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.