SCHEMBL346255

SCHEMBL346255

c1cnc2ccc3cncnc3c2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
MAPT P10636 3/20 0.52
KDM4E B2RXH2 2/20 0.52
CYP3A4 P08684 2/20 0.52
HSP90AA1 P07900 3/20 0.42
HTT P42858 2/20 0.42
HIF1A Q16665 2/20 0.42
MEN1 O00255 1/20 0.42
HSP90AB1 P08238 1/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
EGFR P00533 3/20 0.41
NPC1 O15118 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GMNN O75496 1/20 0.38
TP53 P04637 1/20 0.38
MMP2 P08253 1/20 0.38
CYP2D6 P10635 1/20 0.38
MMP9 P14780 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30432091 0.81 EGFR (0.47) LMNAEGFRTDO2PIK3CDPIK3CA
SCHEMBL27885494 0.81 LMNA (0.96) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL1096307 0.81 EGFR (0.47) LMNAEGFRTDO2PIK3CDPIK3CA
SCHEMBL2362178 0.79 LMNA (0.56) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL6513577 0.79 LMNA (1.00) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL8313 0.79 LMNA (1.00) LMNAMAPTKDM4ECYP3A4HSP90AA1
SCHEMBL9872273 0.79 LMNA (0.65) LMNAMAPTKDM4ECYP3A4HSP90AA1
Cyanide SCHEMBL27332417 0.78 LMNA (0.89) LMNAMAPTKDM4ECYP3A4HSP90AA1
Cyanide SCHEMBL27465941 0.78 LMNA (0.89) LMNAMAPTKDM4ECYP3A4HSP90AA1
Pyrazine SCHEMBL28719971 0.78 LMNA (0.89) LMNAMAPTKDM4ECYP3A4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074310-A1 LIGHT-EMITTING DEVICE, AND DISPLAY APPARATUS AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US claimed
CN-117596910-A Light emitting device, display apparatus including the same, and electronic apparatus 三星显示有限公司 2024-02-23 CN claimed
US-20220216419-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-07-07 US claimed
EP-2336315-B1 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION AS (DK) 2017-07-19 EP claimed
EP-2336315-A2 Enzymatic encoding methods for efficient synthesis of large libraries Nuevolution A/S (DK) 2011-06-22 EP claimed
EP-0944641-B1 NON-HELICAL SUPRAMOLECULAR NANOSYSTEMS NANOGEN RECOGNOMICS GMBH (DE) 2003-07-02 EP claimed
EP-0944641-A1 NON-HELICAL SUPRAMOLECULAR NANOSYSTEMS Nanogen Recognomics GmbH (DE) 1999-09-29 EP claimed
WO-1998025943-A1 NON-HELICAL SUPRAMOLECULAR NANOSYSTEMS AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-06-18 WO claimed
US-12396364-B2 Nitrogen-containing organic compound, use thereof, and organic electroluminescent device using same SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2025-08-19 US disclosed
US-12396364-B2 Nitrogen-containing organic compound, use thereof, and organic electroluminescent device using same SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2025-08-19 US disclosed
CN-220755379-U Light emitting device, display apparatus including the same, and electronic apparatus 三星显示有限公司 2024-04-09 CN disclosed
US-20240074310-A1 LIGHT-EMITTING DEVICE, AND DISPLAY APPARATUS AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
CN-117596910-A Light emitting device, display apparatus including the same, and electronic apparatus 三星显示有限公司 2024-02-23 CN disclosed
CN-115894486-B Hydrogenated pyridoquinazoline compound, composition and application thereof 北京赛特明强医药科技有限公司 2024-02-09 CN disclosed
WO-2007062664-A2 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2007-06-07 WO disclosed
US-20060004028-A1 Novel PARP inhibitor MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 US disclosed
EP-1582520-A1 NOVEL PARP INHIBITORS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2005-10-05 EP disclosed
EP-0944641-B1 NON-HELICAL SUPRAMOLECULAR NANOSYSTEMS NANOGEN RECOGNOMICS GMBH (DE) 2003-07-02 EP disclosed
US-4472399-A Indolo[2',3';3,4]pyrido[2,1-b]quinazoline-5-ones, a process for the preparation thereof, and diuretic compositions and methods using them CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1984-09-18 US disclosed
US-4348396-A Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them HOFFMANN-LA ROCHE INC. (US) 1982-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004028-A1 Novel PARP inhibitor PARP1, PARP2, PARP11 LMNA 666/4885MAPT 497/4885KDM4E 812/4885
US-12396364-B2 Nitrogen-containing organic compound, use thereof, and organic electroluminescent device using same OCIAD2, OCIAD1, NONO LMNA 3076/4885MAPT 793/4885KDM4E 373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.