Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548944 | 0.92 | LMNA (0.59) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL30074407 | 0.92 | LMNA (0.59) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL27885494 | 0.81 | LMNA (0.96) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL30432091 | 0.81 | EGFR (0.47) | LMNAEGFRPIK3CDPIK3CA | |
| SCHEMBL1096307 | 0.81 | EGFR (0.47) | LMNAEGFRPIK3CDPIK3CA | |
| SCHEMBL8313 | 0.79 | LMNA (1.00) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL6513577 | 0.79 | LMNA (1.00) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL346255 | 0.79 | LMNA (0.65) | LMNACCR1CCR5CCR8KDM4E | |
| Pyrazine SCHEMBL28719971 | 0.78 | LMNA (0.89) | LMNACCR1CCR5CCR8KDM4E | |
| Cyanide SCHEMBL27465941 | 0.78 | LMNA (0.89) | LMNACCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019390-A | Method for preparing drug intermediate pyrimido [4,5-b ] quinoline derivative by eutectic solvent catalysis | 南京苏亦欣医药科技有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-116535405-B | Benzimidazole fused pyrimidoquinoline fluorescent molecule, and preparation method and application thereof | 武汉轻工大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-116535405-B | Benzimidazole fused pyrimidoquinoline fluorescent molecule, and preparation method and application thereof | 武汉轻工大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-116535405-B | Benzimidazole fused pyrimidoquinoline fluorescent molecule, and preparation method and application thereof | 武汉轻工大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-116535405-A | Benzimidazole fused pyrimidoquinoline fluorescent molecule, and preparation method and application thereof | 武汉轻工大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-116535405-A | Benzimidazole fused pyrimidoquinoline fluorescent molecule, and preparation method and application thereof | 武汉轻工大学 | 2023-08-04 | — | — | CN | disclosed |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| CN-113185512-B | 5-aminopyrimido [4,5-b ] quinoline compound and preparation method and application thereof | 桂林医学院 | 2023-05-05 | — | — | CN | disclosed |
| CN-113185512-A | 5-aminopyrimidino [4,5-b ] quinoline compound and preparation method and application thereof | 桂林医学院 | 2021-07-30 | — | — | CN | disclosed |
| US-9947877-B2 | Organic light emitting display device | LG DISPLAY CO., LTD. (KR) | 2018-04-17 | — | — | US | disclosed |
| US-9947877-B2 | Organic light emitting display device | LG DISPLAY CO., LTD. (KR) | 2018-04-17 | — | — | US | disclosed |
| US-20160285010-A1 | ORGANIC LIGHT EMITTING DISPLAY DEVICE | LG DISPLAY CO., LTD. (KR) | 2016-09-29 | — | — | US | disclosed |
| US-5070086-A | ANTIALLERGY, ANTIINFLAMMATORY, ANTIPSORIASIS | SCHERING CORPORATION (US) | 1991-12-03 | — | — | US | disclosed |
| US-5070086-A | ANTIALLERGY, ANTIINFLAMMATORY, ANTIPSORIASIS | SCHERING CORPORATION (US) | 1991-12-03 | — | — | US | disclosed |
| US-5070086-A | ANTIALLERGY, ANTIINFLAMMATORY, ANTIPSORIASIS | SCHERING CORPORATION (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0325048-A1 | Imidazo- and pyrimido-quinoline, naphthyridine and pyridopyrazine compounds | SCHERING CORPORATION (US) | 1989-07-26 | — | — | EP | disclosed |
| EP-0325048-A1 | Imidazo- and pyrimido-quinoline, naphthyridine and pyridopyrazine compounds | SCHERING CORPORATION (US) | 1989-07-26 | — | — | EP | disclosed |
| US-4539230-A | COATING WALLS WITH A CHELATE COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | OCIAD1, OCIAD2, EHD1 | LMNA 1600/4885CCR1 3282/4885CCR5 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.