Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637856 | 0.74 | HTR6 (0.64) | HTR6HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL6081154 | 0.74 | GRIN1 (0.45) | PARP1CYP1A2CYP2D6 | |
| SCHEMBL6862876 | 0.74 | HTR6 (0.63) | HTR6HTR2AHTR2CSLC6A4PARP1 | |
| SCHEMBL6079344 | 0.73 | HTR6 (0.47) | HTR6HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL5363679 | 0.71 | GNRHR (0.66) | HTR6HTR2AHTR2CSLC6A4PARP1 | |
| SCHEMBL8143591 | 0.71 | HTR6 (0.50) | HTR6PARP1 | |
| SCHEMBL20449682 | 0.70 | PARP1 (0.56) | HTR6PARP1HTR3A | |
| SCHEMBL30124461 | 0.70 | HTR2A (0.55) | HTR6HTR2AHTR2CSLC6A4HTR1A | |
| Trifluoroacetic Acid SCHEMBL30355123 | 0.69 | HRH4 (0.48) | HTR6HTR2APARP1HTR1AHTR7 | |
| SCHEMBL6596699 | 0.68 | HTR5A (0.47) | HTR6HTR2AHTR2CSLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808583-A | MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | claimed |
| EP-0138018-B1 | SOLUTIONS OF LACTIC ACID SALTS OF PIPERAZINYLQUINOLONE AND PIPERAZINYL AZAQUINOLONECARBOXYLIC ACIDS | BAYER AG (DE) | 1988-11-02 | — | — | EP | claimed |
| WO-2010146478-A1 | PARENTERAL COMPOSITION COMPRISING A FLUOROQUINOLONE COMPOUND AND A NITROIMIDAZOLE COMPOUND | RANBAXY LABORATORIES LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |
| EP-0662833-B1 | AQUEOUS COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5686440-A | CONTAINING LACTIC ACID AS A SOLUBILIZER AND AN ADDITIVE | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-11-11 | — | — | US | disclosed |
| US-5563149-A | INJECTION OR INFUSION SOLUTIONS WITH SOLUBILIZING AGENT | CHEIL FOODS & CHEMICALS, INC. (KR) | 1996-10-08 | — | — | US | disclosed |
| EP-0662833-A1 | AQUEOUS COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |
| WO-1995003802-A1 | AQUEOUS COMPOSITION | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-02-09 | — | — | WO | disclosed |
| US-4808585-A | WITH EXCESS ACID; NONPRECIPITATING | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| US-4808585-A | WITH EXCESS ACID; NONPRECIPITATING | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| US-4808585-A | WITH EXCESS ACID; NONPRECIPITATING | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| US-4808583-A | MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| US-4808583-A | MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| US-4808583-A | MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| US-4705789-A | Solutions of lactic acid salts of piperazinylquinolone- and piperazinyl-azaquinolone-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1987-11-10 | — | — | US | disclosed |
| US-4705789-A | Solutions of lactic acid salts of piperazinylquinolone- and piperazinyl-azaquinolone-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1987-11-10 | — | — | US | disclosed |
| US-4705789-A | Solutions of lactic acid salts of piperazinylquinolone- and piperazinyl-azaquinolone-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1987-11-10 | — | — | US | disclosed |
| EP-0138018-A2 | Solutions of lactic acid salts of piperazinylquinolone and piperazinyl azaquinolonecarboxylic acids | BAYER AG (DE) | 1985-04-24 | — | — | EP | disclosed |