Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28303247 | 0.83 | CA12 (0.48) | L3MBTL1CA12CA1CA7CA14 | |
| SCHEMBL34467582 | 0.80 | CYP2C9 (0.42) | CA12CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11501252 | 0.78 | NPC1 (0.41) | L3MBTL1CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19153323 | 0.77 | HDAC3 (0.52) | L3MBTL1AKT1NPSR1HDAC3HDAC1 | |
| SCHEMBL5368670 | 0.75 | AKT1 (0.53) | L3MBTL1CA12CA1CA7CA14 | |
| SCHEMBL13430499 | 0.75 | L3MBTL1 (0.39) | L3MBTL1CA12CA1CA7CA14 | |
| SCHEMBL4521331 | 0.75 | L3MBTL1 (0.47) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL8708800 | 0.73 | ATM (0.44) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL8708798 | 0.73 | ATM (0.44) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL3463436 | 0.72 | SMN1; SMN2 (0.43) | L3MBTL1ATMCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |