Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443262 | 0.78 | RIPK1 (0.47) | SMN1; SMN2L3MBTL1LMNARIPK1RAB9A | |
| SCHEMBL4958456 | 0.74 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1CASP1CYP3A4ALDH1A1 | |
| SCHEMBL8174092 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL7624194 | 0.72 | CASP1 (0.68) | CASP1CYP3A4ALDH1A1CYP2C19LMNA | |
| SCHEMBL3463439 | 0.72 | L3MBTL1 (0.44) | L3MBTL1CYP3A4ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4959369 | 0.71 | CYP3A4 (0.49) | SMN1; SMN2L3MBTL1CASP1CYP3A4ALDH1A1 | |
| SCHEMBL9488110 | 0.70 | LMNA (0.55) | SMN1; SMN2L3MBTL1CYP3A4ALDH1A1LMNA | |
| SCHEMBL3463370 | 0.70 | CASP1 (0.52) | SMN1; SMN2CASP1CYP3A4ALDH1A1MAPT | |
| SCHEMBL11002529 | 0.70 | CASP1 (0.49) | SMN1; SMN2L3MBTL1CASP1CYP3A4ALDH1A1 | |
| SCHEMBL6866251 | 0.70 | CYP3A4 (0.51) | SMN1; SMN2L3MBTL1CASP1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |