Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708800 | 1.00 | ATM (0.44) | ATMITGA4ITGB7KLK5LAP3 | |
| SCHEMBL8709246 | 0.84 | REN (0.42) | ATMKLK5 | |
| SCHEMBL8709243 | 0.84 | REN (0.42) | ATMKLK5 | |
| SCHEMBL8711623 | 0.84 | REN (0.42) | ATMKLK5 | |
| SCHEMBL8713524 | 0.82 | TRPM8 (0.52) | ATMKLK5PSEN1PSEN2APH1B | |
| SCHEMBL8713521 | 0.82 | TRPM8 (0.52) | ATMKLK5PSEN1PSEN2APH1B | |
| SCHEMBL8268266 | 0.82 | CSNK1E (0.43) | ATMITGA4ITGB7KLK5LAP3 | |
| SCHEMBL13219388 | 0.82 | CSNK1E (0.43) | ATMITGA4ITGB7KLK5LAP3 | |
| SCHEMBL8708735 | 0.81 | KLK5 (0.51) | ATMKLK5PSEN1PSEN2APH1B | |
| SCHEMBL8708738 | 0.81 | KLK5 (0.51) | ATMKLK5PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |