SCHEMBL3463622

SCHEMBL3463622

CCCC1(COS(C)(=O)=O)COC1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.32
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MMP9 P14780 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3462915 0.86 PRKCA (0.39) PRKCAKDM4EUSP2ALDH1A1LMNA
SCHEMBL1039373 0.85 TSHR (0.34) PRKCAKDM4EUSP2ALDH1A1LMNA
SCHEMBL12027551 0.84 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL14481104 0.79 KDM4E (0.32) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL2572008 0.76 EPHX1 (0.32)
SCHEMBL16454445 0.75 USP2 (0.44) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL3462927 0.74 KDM4E (0.40) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL16766 0.72 EPHX1 (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL2825426 0.72 EPHX1 (0.30)
SCHEMBL5945110 0.72 EPHX1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2204388-B1 PROCESS FOR THE PRODUCTION OF WATER-ABSORBING RESINS AND WATER-ABSORBING RESINS OBTAINED BY THE PROCESS SUMITOMO SEIKA CHEMICALS (JP) 2012-11-21 EP disclosed
EP-2204388-A1 PROCESS FOR THE PRODUCTION OF WATER-ABSORBING RESINS AND WATER-ABSORBING RESINS OBTAINED BY THE PROCESS Sumitomo Seika Chemicals CO. LTD. (JP) 2010-07-07 EP disclosed
US-5466710-A Heterobicycloalkanes as pesticidal compounds ROUSSEL UCLAF (FR) 1995-11-14 US disclosed
EP-0300797-B1 Pesticidal compounds ROUSSEL UCLAF (FR) 1995-10-04 EP disclosed
US-5116862-A Acetylenic trithiabicyclo(2.2.2)octanes THE WELLCOME FOUNDATION LIMITED (GB) 1992-05-26 US disclosed
US-5026874-A Agricultural insecticides WELLCOME FOUNDATION LIMITED (GB) 1991-06-25 US disclosed
EP-0300797-A1 Pesticidal compounds ROUSSEL UCLAF (FR) 1989-01-25 EP disclosed