SCHEMBL16766

SCHEMBL16766

CC1(COS(C)(=O)=O)COC1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.39
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MMP9 P14780 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711066 0.92 KDM4E (0.33) EPHX1KDM4EUSP2ALDH1A1LMNA
SCHEMBL14891993 0.83 KDM4E (0.33) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL3463025 0.81 EPHX1 (0.38) EPHX1PTGS2
SCHEMBL14924188 0.79 USP2 (0.40) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL18256712 0.79 AOC2 (0.34) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL3462689 0.79 KDM4E (0.43) EPHX1KDM4EUSP2ALDH1A1LMNA
SCHEMBL21798069 0.79 EPHX1 (0.31) EPHX1
SCHEMBL3462696 0.78 EPHX1 (0.35) EPHX1
SCHEMBL15108053 0.77 KDM4E (0.34) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL18256646 0.77 KDM4E (0.34) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118943463-A Secondary battery, method for manufacturing the same, and electronic device 宁德新能源科技有限公司 2024-11-12 CN claimed
WO-2024211274-A1 FUNCTIONALIZED CYCLIC ETHERS FOR LITHIUM-ION BATTERIES NOHMs Technologies, Inc. (US) 2024-10-10 WO claimed
US-20240339662-A1 FUNCTIONALIZED CYCLIC ETHERS FOR LITHIUM-ION BATTERIES NOHMs Technologies, Inc. (US) 2024-10-10 US claimed
EP-4288426-B1 QUINOXALINE DERIVATIVES AND USES THEREOF BLACK DIAMOND THERAPEUTICS INC (US) 2026-02-04 EP disclosed
EP-4303978-B1 ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME SK ON CO LTD (KR) 2025-01-29 EP disclosed
CN-118943463-A Secondary battery, method for manufacturing the same, and electronic device 宁德新能源科技有限公司 2024-11-12 CN disclosed
US-20240368181-A1 QUINOXALINE DERIVATIVES AND USES THEREOF BLACK DIAMOND THERAPEUTICS, INC. (US) 2024-11-07 US disclosed
WO-2024211274-A1 FUNCTIONALIZED CYCLIC ETHERS FOR LITHIUM-ION BATTERIES NOHMs Technologies, Inc. (US) 2024-10-10 WO disclosed
US-20240339662-A1 FUNCTIONALIZED CYCLIC ETHERS FOR LITHIUM-ION BATTERIES NOHMs Technologies, Inc. (US) 2024-10-10 US disclosed
US-12060357-B2 9-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use MERCK SHARP & DOHME LLC (US) 2024-08-13 US disclosed
US-12027669-B2 Electrolyte solution for lithium secondary battery and lithium secondary battery including the same SK ON CO., LTD. (KR) 2024-07-02 US disclosed
US-20100075948-A1 Substituted Pyrrolidine-2-Carboxamides DING QINGJIE 2010-03-25 US disclosed
EP-1486501-B1 AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE ASTELLAS PHARMA INC (JP) 2008-09-10 EP disclosed
WO-2007143847-A1 SPIROTROPANE COMPOUNDS VIROCHEM PHARMA INC. (CA) 2007-12-21 WO disclosed
US-7250429-B2 Aminomethyl-substituted thiazolobenzimidazole compounds ASTELLAS PHARMA INC. (JP) 2007-07-31 US disclosed
US-20070088032-A1 Processes for the Preparation of Benzoimidazole Derivatives TOM NORMA J 2007-04-19 US disclosed
US-7183414-B2 Processes for the preparation of benzoimidazole derivatives PFIZER INC (US) 2007-02-27 US disclosed
US-7183414-B2 Processes for the preparation of benzoimidazole derivatives PFIZER INC (US) 2007-02-27 US disclosed
US-20050148642-A1 Aminomethyl-substituted thiazolobenzimidazole derivative ASTELLAS PHARMA INC. (JP) 2005-07-07 US disclosed
EP-1486501-A1 AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 2004-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12060357-B2 9-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use ADORA2A, ADORA2B, ADORA3 EPHX1 1521/4885KDM4E 3535/4885USP2 3645/4885
US-20050148642-A1 Aminomethyl-substituted thiazolobenzimidazole derivative GRM1, GRIN1, GRM3 EPHX1 2482/4885KDM4E 1650/4885USP2 3686/4885
US-20070088032-A1 Processes for the Preparation of Benzoimidazole Derivatives CCNI, CCNT1, CCNE1 EPHX1 2392/4885KDM4E 739/4885USP2 3794/4885
US-20240339662-A1 FUNCTIONALIZED CYCLIC ETHERS FOR LITHIUM-ION BATTERIES SELE, CYCS, EPCAM EPHX1 1386/4885KDM4E 249/4885USP2 3534/4885
US-20100075948-A1 Substituted Pyrrolidine-2-Carboxamides ARG2, CCNY, PYCR1 EPHX1 3073/4885KDM4E 272/4885USP2 2449/4885
US-20240368181-A1 QUINOXALINE DERIVATIVES AND USES THEREOF NQO2, NQO1, GLS EPHX1 1826/4885KDM4E 2187/4885USP2 4301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.