Ambrosin

Ambrosin

SCHEMBL3463664

C=C1C(=O)OC2C1CCC(C)C1C=CC(=O)C12C

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.54
▸ RAB9A P51151 6/20 0.54
▸ NPC1 O15118 5/20 0.54
▸ HTT P42858 5/20 0.54
▸ POLB P06746 4/20 0.54
▸ MAPK1 P28482 4/20 0.54
▸ ALDH1A1 P00352 4/20 0.54
▸ XBP1 P17861 3/20 0.54
▸ MDM2 Q00987 3/20 0.54
▸ AGTR1 P30556 3/20 0.54
▸ GPR55 Q9Y2T6 3/20 0.54
▸ TERT O14746 1/20 0.54
▸ GLA P06280 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ KMT2A Q03164 2/20 0.53
▸ RECQL P46063 2/20 0.47
▸ PKM P14618 2/20 0.47
▸ PAX8 Q06710 2/20 0.47
▸ THRB P10828 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ambrosin SCHEMBL3463663 1.00 MAPT (0.54) MAPTRAB9ANPC1HTTPOLB
Damsin SCHEMBL18642934 0.73 PTGS2 (0.55) MAPTRAB9ANPC1HTTMAPK1
Damsin SCHEMBL18642932 0.73 PTGS2 (0.55) MAPTRAB9ANPC1HTTMAPK1
Helenalin SCHEMBL11030579 0.70 MAPT (1.00) MAPTRAB9ANPC1HTTPOLB
Helenalin SCHEMBL10132557 0.70 MAPT (1.00) MAPTRAB9ANPC1HTTPOLB
Helenalin SCHEMBL161594 0.70 MAPT (1.00) MAPTRAB9ANPC1HTTPOLB
Helenalin SCHEMBL161593 0.70 MAPT (1.00) MAPTRAB9ANPC1HTTPOLB
Helenalin SCHEMBL31237389 0.70 MAPT (1.00) MAPTRAB9ANPC1HTTPOLB
Helenalin SCHEMBL10099625 0.70 MAPT (1.00) MAPTRAB9ANPC1HTTPOLB
Mexicanin I SCHEMBL17238871 0.70 MAPT (1.00) MAPTRAB9ANPC1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3349584-B1 MEDICINAL AMBROSIA PLANT EXTRACTS EL SAWY MOHAMED FAKHR EL DIN (EG) 2025-07-16 — — EP claimed
US-11911428-B2 Medicinal ambrosia maritima extracts HELMY SHERINE HASSAN ABBAS (EG) 2024-02-27 — — US claimed
US-20220362321-A1 MEDICINAL AMBROSIA MARITIMA EXTRACTS HELMY SHERINE HASSAN ABBAS (EG) 2022-11-17 — — US claimed
US-10653739-B2 Medicinal ambrosia maritima extracts EL SAWY MOHAMED FAKHR EL DIN (EG) 2020-05-19 — — US claimed
CN-108348561-A Extract of ragweed plant 穆罕默德·法赫尔·埃尔-丁·埃尔-萨维 2018-07-31 — — CN claimed
EP-3349584-A1 MEDICINAL AMBROSIA PLANT EXTRACTS El-Sawy, Mohamed Fakhr El-Din (EG) 2018-07-25 — — EP claimed
WO-2017044860-A1 MEDICINAL AMBROSIA PLANT EXTRACTS EL-SAWY MOHAMED FAKHR EL-DIN (EG) 2017-03-16 — — WO claimed
US-20170071994-A1 MEDICINAL AMBROSIA MARITIMA EXTRACTS EL-SAWY MOHAMED FAKHR EL-DIN (EG) 2017-03-16 — — US claimed
EP-3349584-B1 MEDICINAL AMBROSIA PLANT EXTRACTS EL SAWY MOHAMED FAKHR EL DIN (EG) 2025-07-16 — — EP disclosed
US-11911428-B2 Medicinal ambrosia maritima extracts HELMY SHERINE HASSAN ABBAS (EG) 2024-02-27 — — US disclosed
US-20220362321-A1 MEDICINAL AMBROSIA MARITIMA EXTRACTS HELMY SHERINE HASSAN ABBAS (EG) 2022-11-17 — — US disclosed
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS PURDUE RESEARCH FOUNDATION (US) 2021-10-14 — — US disclosed
CN-111565716-A Methods of using dipivefrin 因斯格尼斯疗法有限公司 2020-08-21 — — CN disclosed
US-20200222485-A1 MEDICINAL AMBROSIA PLANT EXTRACTS EL SAWY MOHAMED FAKHR EL DIN (EG) 2020-07-16 — — US disclosed
EP-0980262-A1 SOLID PHARMACEUTICAL FORMULATIONS CONTAINING A PHYSICAL MIXTURE OF SULFOALKYL ETHER CYCLODEXTRIN AND A THERAPEUTIC AGENT Cydex Inc. (US) 2000-02-23 — — EP disclosed
US-5981577-A ANTITUMOR ACTIVITY DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) 1999-11-09 — — US disclosed
WO-1999035150-A1 SYNTHESIS OF COMBRETASTATIN A-4 PRODRUGS AND TRANS-ISOMERS THEREO F ARIZONA BOARD OF REGENTS, A BODY CORPORATE, ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 1999-07-15 — — WO disclosed
US-5905089-A USEFUL IN SUPPRESSING EARLY PROINFLAMMATORY CYTOKINES AND IN AMELIORATING SEPTIC SHOCK AND OTHER SEVERE INFLAMMATORY DISORDERS BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 1999-05-18 — — US disclosed
US-5874418-A SUSTAINED RELEASE CYDEX, INC. (US) 1999-02-23 — — US disclosed
WO-1998050077-A1 SOLID PHARMACEUTICAL FORMULATIONS CONTAINING A PHYSICAL MIXTURE OF SULFOALKYL ETHER CYCLODEXTRIN AND A THERAPEUTIC AGENT CYDEX INC. (US) 1998-11-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS MIF, LTA, MGAM MAPT 3922/4885RAB9A 3395/4885NPC1 4363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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