Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSH | P09668 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525228 | 0.80 | KMT2A (0.61) | KMT2AOPRK1KDM4EUSP2HPGD | |
| Hydrochloric Acid SCHEMBL11130882 | 0.79 | KMT2A (0.59) | KMT2AOPRK1KDM4EUSP2HPGD | |
| Hydrochloric Acid SCHEMBL30894755 | 0.79 | KMT2A (0.59) | KMT2AOPRK1KDM4EUSP2HPGD | |
| SCHEMBL3275602 | 0.77 | KMT2A (0.77) | KMT2AOPRK1KDM4EUSP2HPGD | |
| SCHEMBL1461233 | 0.76 | KMT2A (0.56) | KMT2AOPRK1KDM4EUSP2HPGD | |
| SCHEMBL7171554 | 0.75 | KMT2A (0.74) | KMT2AOPRK1KDM4EUSP2HPGD | |
| SCHEMBL8090833 | 0.73 | KMT2A (1.00) | KMT2AOPRK1KDM4EUSP2HPGD | |
| SCHEMBL29152656 | 0.72 | KMT2A (0.50) | KMT2AOPRK1KDM4ECTSBCTSH | |
| SCHEMBL20706341 | 0.71 | ALDH1A1 (0.46) | KMT2AKDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL12250777 | 0.71 | KDM4E (0.50) | KDM4EUSP2HPGDHSD17B10GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470208-B2 | Organometallic complexes | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470208-B2 | Organometallic complexes | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470208-B2 | Organometallic complexes | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-25 | — | — | US | disclosed |
| EP-1979437-B1 | ORGANOMETALLIC COMPLEXES | DU PONT (US) | 2013-04-10 | — | — | EP | disclosed |
| EP-1979437-B1 | ORGANOMETALLIC COMPLEXES | DU PONT (US) | 2013-04-10 | — | — | EP | disclosed |
| US-20100264380-A1 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| US-20100264380-A1 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| US-20100264380-A1 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| CN-101370904-A | Organometallic complexes | DU PONT (US) | 2009-02-18 | — | — | CN | disclosed |
| EP-1979437-A2 | ORGANOMETALLIC COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007087223-A2 | ORGANOMETALLIC COMPLEXES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007087223-A2 | ORGANOMETALLIC COMPLEXES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100264380-A1 | Organometallic complexes | GSTO1, CYP4F12, CYP4F3 | KMT2A 369/4885OPRK1 2075/4885KDM4E 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.