Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464504 | 0.81 | CYP19A1 (0.39) | CYP19A1CYP11B2 | |
| SCHEMBL1129687 | 0.67 | DRD2 (0.31) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL733033 | 0.66 | ESR1 (0.34) | CYP19A1CYP11B2 | |
| SCHEMBL3465175 | 0.66 | CYP19A1 (0.56) | CYP19A1CYP11B2 | |
| SCHEMBL3465912 | 0.65 | CYP19A1 (0.55) | CYP19A1CYP11B2 | |
| SCHEMBL4641520 | 0.63 | MAP3K14 (0.42) | MAOAMAOBMAP3K14DRD2DRD1 | |
| SCHEMBL3464633 | 0.62 | MAOA (0.41) | MAOAMAOBMAP3K14 | |
| SCHEMBL1129533 | 0.59 | GRM4 (0.32) | — | |
| SCHEMBL8699804 | 0.58 | MAOA (0.49) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL29598243 | 0.58 | MAOA (0.49) | MAOAMAOBDRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168145-A1 | FUSED IMIDAZOLE DERIVATIVES AND USE THEREOF AS ALDOSTERONE SYNTHASE INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168145-A1 | FUSED IMIDAZOLE DERIVATIVES AND USE THEREOF AS ALDOSTERONE SYNTHASE INHIBITORS | CYP21A2, CYP11B1, CYP17A1 | CYP19A1 37/4885MAOA 322/4885MAOB 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.