Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29598243 | 1.00 | MAOA (0.49) | MAOAMAOBDRD2DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL28232988 | 0.98 | MAOA (0.47) | MAOAMAOBDRD2DRD1DRD4 | |
| Formaldehyde SCHEMBL27689991 | 0.94 | MAOA (0.49) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL281673 | 0.88 | MAOA (0.56) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL27619324 | 0.85 | HSD17B1 (0.45) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29674920 | 0.84 | CTNNB1 (0.49) | MAOAMAOBCYP3A4ESR2ESR1 | |
| SCHEMBL459693 | 0.84 | CTNNB1 (0.49) | MAOAMAOBCYP3A4ESR2ESR1 | |
| SCHEMBL28874219 | 0.82 | CTNNB1 (0.48) | MAOAMAOBCYP3A4ESR2ESR1 | |
| Ethoxycarbonyl Group SCHEMBL27889131 | 0.81 | CTNNB1 (0.41) | MAOAMAOBDRD2DRD1DRD4 | |
| SCHEMBL23259146 | 0.78 | CTNNB1 (0.40) | MAOAMAOBCTNNB1WNT3APRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101618033-A | New medical application of chromane compound HEF-05 | UNIV SHENYANG PHARMACEUTICAL | 2010-01-06 | — | — | CN | claimed |
| EP-0515388-B1 | PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING A STABILISER COMPOUND | KODAK LTD (GB) | 1993-11-18 | — | — | EP | claimed |
| EP-0515388-A1 | PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING A STABILISER COMPOUND. | KODAK LTD (GB) | 1992-12-02 | — | — | EP | claimed |
| WO-1991011749-A1 | PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING A STABILISER COMPOUND | KODAK LIMITED (GB) | 1991-08-08 | — | — | WO | claimed |
| CN-118344325-A | PI3K selective inhibitors | 轩竹生物科技股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20230233519-A1 | COMBINATION THERAPIES | Aardvark Therapeutics, Inc. | 2023-07-27 | — | — | US | disclosed |
| WO-2023007941-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SPECIFIC COPOLYMER | 日産化学株式会社 | 2023-02-02 | — | — | WO | disclosed |
| WO-2023007972-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION | 日産化学株式会社 | 2023-02-02 | — | — | WO | disclosed |
| US-11261178-B2 | Chroman derivatives having estrogen receptor degradation activity and uses thereof | ACCUTAR BIOTECHNOLOGY INC. (US) | 2022-03-01 | — | — | US | disclosed |
| EP-3911690-A1 | PROCESS FOR PRODUCING DIOL | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-11-24 | — | — | EP | disclosed |
| EP-3810674-A1 | PROCESS FOR PRODUCING POLYOL | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-04-28 | — | — | EP | disclosed |
| EP-2981260-B1 | NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS | SPHAERA PHARMA PRIVATE LTD (IN) | 2021-01-13 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| US-4780478-A | Aminopropoxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 1988-10-25 | — | — | US | disclosed |
| US-4508732-A | Basic ethers useful as antidepressant agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-02 | — | — | US | disclosed |
| EP-0031885-B1 | BASIC ETHERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | MERCK PATENT GmbH (DE) | 1984-06-27 | — | — | EP | disclosed |
| US-4391821-A | HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS, ANTIARRHYTHMIA AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1983-07-05 | — | — | US | disclosed |
| US-4376123-A | Hexahydroazepinyloxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-03-08 | — | — | US | disclosed |
| EP-0031885-A1 | Basic ethers, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-3957763-A | PHENYL DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261178-B2 | Chroman derivatives having estrogen receptor degradation activity and uses thereof | ESR1, ESR2, ESRRG | MAOA 571/4885MAOB 866/4885DRD2 3624/4885 |
| US-20230233519-A1 | COMBINATION THERAPIES | BCL2, BAK1, BCL2L2 | MAOA 3950/4885MAOB 2663/4885DRD2 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.