SCHEMBL3464612

SCHEMBL3464612

CCCOc1ccccc1[N+](=O)[O-]

nearest known ligand 0.79

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.79
RAB9A P51151 3/20 0.79
RECQL P46063 2/20 0.79
ALDH1A1 P00352 7/20 0.69
LMNA P02545 2/20 0.69
KMT2A Q03164 4/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
MAPT P10636 4/20 0.64
MEN1 O00255 2/20 0.64
MAPK1 P28482 1/20 0.64
TDP1 Q9NUW8 1/20 0.59
HTT P42858 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.57
KDM4E B2RXH2 1/20 0.56
HPGD P15428 2/20 0.55
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL514901 0.97 NPC1 (0.74) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL3463529 0.91 NPC1 (0.77) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL28092385 0.91 NPC1 (0.66) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL19559223 0.90 ALDH1A1 (0.81) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL1340160 0.90 NPC1 (0.74) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL9187561 0.89 NPC1 (1.00) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL1123538 0.88 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL8581954 0.88 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL50769 0.88 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA
SCHEMBL2304857 0.88 NPC1 (0.72) NPC1RAB9ARECQLALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107469813-B A kind of carried noble metal hydrogenation catalyst and its preparation and application 浙江工业大学 2019-11-29 CN claimed
CN-107469813-A A kind of carried noble metal hydrogenation catalyst and its preparation and application 浙江工业大学 2017-12-15 CN claimed
US-20100224030-A1 INDIUM RECOVERY BY SUPPORTED LIQUID MEMBRANE WITH STRIP DISPERSION CHUNG YUAN CHRISTIAN UNIVERSITY (TW) 2010-09-09 US claimed
CN-100494159-C Process of producing nitrobenzether aminobenzether amidobenzether from chlorobenzene JIASEN CHEMICAL INDUSTRY CO LT (CN) 2009-06-03 CN claimed
CN-100357256-C Method for synthesizing o-aminophenylpropyl alcohol UNIV SHANGHAI (CN) 2007-12-26 CN claimed
CN-1861562-A Process of producing nitrobenzether aminobenzether amidobenzether from chlorobenzene JIASEN CHEMICAL INDUSTRY CO LT (CN) 2006-11-15 CN claimed
CN-1760173-A Method for synthesizing o-aminophenylpropyl alcohol UNIV SHANGHAI (CN) 2006-04-19 CN claimed
US-6433163-B1 EXTRACTION, SEPARATION COMMODORE SEPARATION TECHNOLIGIES, INC. 2002-08-13 US claimed
US-6350419-B1 SUPPORTED LIQUID MEMBRANE/ STRIP DISPERSION FOR REMOVAL OF METALS COMMODORE SEPARATION TECHNOLOGIES INC. 2002-02-26 US claimed
US-6328782-B1 TREATING FEED SOLUTION CONTAINING RADIONUCLIDES OR METALS BY PASSING FEED SOLUTION ON ONE SIDE OF SUPPORTED LIQUID MEMBRANE EMBEDDED IN MICROPOROUS SUPPORT AND REMOVING RADIONUCLIDES BY USE OF STRIP DISPERSION ON OTHER SIDE OF MEMBRANE; SEPARATION COMMODORE SEPARATION TECHNOLOGIES, INC. 2001-12-11 US claimed
US-20010029810-A1 Alkyl phenylphosphonic acid extractants and processes for their manufacture HO W S WINSTON (US) 2001-10-18 US claimed
WO-2001056933-A2 COMBINED SUPPORTED LIQUID MEMBRANE/STRIP DISPERSION PROCESSES AND EXTRACTANTS COMMODORE SEPARATION TECHNOLOGIES, INC. (US) 2001-08-09 WO claimed
US-6171563-B1 Supported liquid membrane process for chromium removal and recovery COMMODORE SEPARATION TECHNOLOGIES, INC. 2001-01-09 US claimed
JP-11080145-A None JP disclosed
JP-56020549-A None JP disclosed
EP-4323350-A1 ISOINDOLINONE COMPOUNDS Monte Rosa Therapeutics AG (CH) 2024-02-21 EP disclosed
EP-0335274-A2 Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1989-10-04 EP disclosed
US-4345937-A Herbicidal N-(haloacetyl)-N-(N'-methylenepyrrolidonyl)-2-alkoxyanilines GAF CORPORATION (US) 1982-08-24 US disclosed
JP-S5620549-A OMEGA-FLUOROPROPOXYNITROBENZENE AND ITS PREPARATION IHARA CHEM IND CO LTD 1981-02-26 JP disclosed
US-4178167-A Herbicidal N-(haloacetyl)-N-(N'-methylenepyrrolidonyl)-2-alkoxyanilines useful as herbicides GAF CORPORATION (US) 1979-12-11 US disclosed