Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 2/20 | 0.91 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.91 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.80 |
| ▸ | DRD1 | P21728 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237191 | 1.00 | HSPD1 (0.91) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| SCHEMBL19708888 | 1.00 | HSPD1 (0.91) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| SCHEMBL3913613 | 1.00 | HSPD1 (0.91) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| Eprinomectin SCHEMBL120548 | 0.97 | HSPD1 (0.98) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| Eprinomectin SCHEMBL29392105 | 0.97 | HSPD1 (0.98) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| SCHEMBL248270 | 0.96 | HSPD1 (1.00) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| SCHEMBL248559 | 0.96 | HSPD1 (1.00) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| SCHEMBL29355814 | 0.96 | HSPD1 (1.00) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| SCHEMBL19708763 | 0.96 | HSPD1 (1.00) | HSPD1HSPE1ADORA3DRD1MEN1 | |
| SCHEMBL29523079 | 0.96 | HSPD1 (1.00) | HSPD1HSPE1ADORA3DRD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2891403-B1 | CHEMICAL AGENT FOR CONTROLLING SOIL NEMATODE WHICH COMPRISES MACROLIDE-TYPE COMPOUND | MARUWA BIOCHEMICAL CO LTD (JP) | 2019-07-24 | — | — | EP | claimed |
| US-20170360029-A1 | Chemical Agent For Controlling Soil Nematode Which Comprises Macrolide-Type Compound | MARUWA BIOCHEMICAL CO., LTD. (JP) | 2017-12-21 | — | — | US | claimed |
| US-20150223449-A1 | Chemical Agent For Controlling Soil Nematode Which Comprises Macrolide-Type Compound | MARUWA BIOCHEMICAL CO., LTD. (JP) | 2015-08-13 | — | — | US | claimed |
| EP-2891403-A1 | CHEMICAL AGENT FOR CONTROLLING SOIL NEMATODE WHICH COMPRISES MACROLIDE-TYPE COMPOUND | Maruwa Biochemical Co., Ltd. (JP) | 2015-07-08 | — | — | EP | claimed |
| EP-2662075-B1 | Taste masking compositions of praziquantel | LAVET GYOGYSZERGYARTO ES SZOLGALTATO KFT (HU) | 2023-02-22 | — | — | EP | disclosed |
| CN-110494129-B | Acetaminoavermectin nanoemulsion and preparation method and application thereof | 江苏龙灯化学有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-110494129-A | A kind of acetylamino evericin nano-emulsion and its preparation method and application | JIANGSU ROTAM CHEMISTRY CO LTD | 2019-11-22 | — | — | CN | disclosed |
| EP-2891403-B1 | CHEMICAL AGENT FOR CONTROLLING SOIL NEMATODE WHICH COMPRISES MACROLIDE-TYPE COMPOUND | MARUWA BIOCHEMICAL CO LTD (JP) | 2019-07-24 | — | — | EP | disclosed |
| US-20180360044-A1 | METHOD FOR THE PROTECTION OF TREES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-20 | — | — | US | disclosed |
| EP-1863496-B1 | METHOD FOR THE PROTECTION OF TREES | TEXAS A & M UNIV SYS (US) | 2018-10-31 | — | — | EP | disclosed |
| US-10058098-B2 | Method for the protection of trees | THE TEXAS A&M UNIVERSITY SYSTEM OFFICE OF TECHNOLOGY COMMERCIALIZATION (US) | 2018-08-28 | — | — | US | disclosed |
| US-9980479-B2 | Method of reducing nematode damage | SYNGENTA CROP PROTECTION, LLC (US) | 2018-05-29 | — | — | US | disclosed |
| CN-100496246-C | Methods of reducing nematode damage | SYNGENTA PARTICIPATIONS AG (CH) | 2009-06-10 | — | — | CN | disclosed |
| US-20080254013-A1 | Using chelate agent and macrocyclic lactone to prevent parasitic worm infection of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| CN-101175500-A | Method for protecting trees | TEXAS A & M UNIV SYS US (US) | 2008-05-07 | — | — | CN | disclosed |
| EP-1863496-A2 | METHOD FOR THE PROTECTION OF TREES | The Texas A&M University System (US) | 2007-12-12 | — | — | EP | disclosed |
| CN-1964628-A | Methods of reducing nematode damage | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-16 | — | — | CN | disclosed |
| EP-1765079-A1 | METHODS OF REDUCING NEMATODE DAMAGE | Syngeta Participations AG (CH) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006102285-A2 | METHOD FOR THE PROTECTION OF TREES | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2006-09-28 | — | — | WO | disclosed |
| WO-2005120232-A1 | METHODS OF REDUCING NEMATODE DAMAGE | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10058098-B2 | Method for the protection of trees | CYCS, LSS, CYP51A1 | HSPD1 978/4885HSPE1 674/4885ADORA3 4137/4885 |
| US-20080254013-A1 | Using chelate agent and macrocyclic lactone to prevent parasitic worm infection of plants | GMNN, DDT, CTSA | HSPD1 1388/4885HSPE1 1028/4885ADORA3 3252/4885 |
| US-20180360044-A1 | METHOD FOR THE PROTECTION OF TREES | CYCS, LSS, CYP51A1 | HSPD1 978/4885HSPE1 674/4885ADORA3 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.