SCHEMBL3465052

SCHEMBL3465052

COC(=O)CCc1cc(C(C)(C)C)c(O)cc1C(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.54
ALOX15 P16050 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP1A2 P05177 1/20 0.47
MAPT P10636 1/20 0.47
ATP2A2 P16615 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ATP2A3 Q93084 1/20 0.47
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
VCAM1 P19320 1/20 0.44
PTGS1 P23219 1/20 0.40
KMT2A Q03164 1/20 0.38
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
TSHR P16473 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10774745 0.88 GAA (0.43) GAAALOX15ALDH1A1KDM4ECYP1A2
SCHEMBL6767978 0.84 GAA (0.51) GAAALOX15ALDH1A1KDM4ECYP1A2
SCHEMBL7691047 0.83 GAA (0.56) GAAALOX15ALDH1A1KDM4ECYP1A2
SCHEMBL10704454 0.82 GAA (0.50) GAAALOX15ALDH1A1KDM4ECYP1A2
SCHEMBL2136221 0.82 GAA (0.50) GAAALOX15ALDH1A1KDM4ECYP1A2
SCHEMBL692695 0.82 GAA (0.58) GAAALOX15ALDH1A1KDM4ECYP1A2
SCHEMBL10691039 0.80 GAA (0.48) GAAALOX15ALDH1A1KDM4ECYP1A2
SCHEMBL7157589 0.80 MIF (0.43) GAAALOX15ALDH1A1KDM4ELMNA
SCHEMBL9224061 0.79 VCAM1 (0.48) GAAALDH1A1SMN1; SMN2LMNAVCAM1
SCHEMBL10749478 0.78 GAA (0.46) GAAALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304477-B2 Liquid oxyalkylene bridged bis- and Tris-phosphite ester mixtures BASF SE (DE) 2012-11-06 US disclosed
EP-2313421-B1 LIQUID OXYALKYLENE BRIDGED BIS- AND TRIS-PHOSPHITE ESTER MIXTURES BASF SE (DE) 2012-08-15 EP disclosed
US-20100240810-A1 Liquid Oxyalkylene Bridged Bis- andTris-Phosphite Ester Mixtures KING ROSWELL E 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240810-A1 Liquid Oxyalkylene Bridged Bis- andTris-Phosphite Ester Mixtures EPB41, PHOSPHO1, TNS4 GAA 4815/4885ALOX15 1421/4885ALDH1A1 4357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.