Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.40 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2136221 | 0.86 | GAA (0.50) | GAAALDH1A1SMN1; SMN2ALOX15KDM4E | |
| SCHEMBL6767978 | 0.82 | GAA (0.51) | GAAALDH1A1SMN1; SMN2ALOX15KDM4E | |
| SCHEMBL10704454 | 0.81 | GAA (0.50) | GAAALDH1A1SMN1; SMN2ALOX15KDM4E | |
| SCHEMBL9713873 | 0.81 | APP (0.48) | GAAALDH1A1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL3465052 | 0.80 | GAA (0.54) | GAAALDH1A1SMN1; SMN2ALOX15KDM4E | |
| SCHEMBL29288496 | 0.80 | TSHR (0.36) | GAAALDH1A1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL89135 | 0.80 | PKM (0.38) | GAAALDH1A1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL8772913 | 0.80 | TSHR (0.38) | GAAALDH1A1SMN1; SMN2CYP1A2TSHR | |
| SCHEMBL175628 | 0.78 | GAA (0.52) | GAAALDH1A1SMN1; SMN2ALOX15CYP1A2 | |
| SCHEMBL10749478 | 0.77 | GAA (0.46) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174277-B1 | ANTI-OXIDANT COMPOSITONS FOR ORGANIC MATERIAL | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| EP-0174277-A1 | Anti-oxidant compositons for organic material | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |