Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7240605 | 0.89 | GAA (0.41) | GAAALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL10704454 | 0.84 | GAA (0.50) | GAAALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL3465052 | 0.84 | GAA (0.54) | GAAALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL10691039 | 0.82 | GAA (0.48) | GAAALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL6712918 | 0.80 | GAA (0.46) | GAAALDH1A1 | |
| SCHEMBL10749478 | 0.80 | GAA (0.46) | GAAALDH1A1 | |
| SCHEMBL9487932 | 0.80 | APP (0.52) | GAAALOX15ALDH1A1LMNAAPP | |
| SCHEMBL2136221 | 0.79 | GAA (0.50) | GAAALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL692695 | 0.79 | GAA (0.58) | GAAALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL3400004 | 0.78 | GAA (0.43) | GAAALOX15ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040210078-A1 | Satbilisation of ethylenically-unsaturated compounds with amidoximes | SUTORIS HEINZ FRIEDRICH | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210078-A1 | Satbilisation of ethylenically-unsaturated compounds with amidoximes | PNMT, NIT2, NNMT | GAA 3181/4885ALOX15 42/4885ALDH1A1 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.