Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924858 | 1.00 | RORC (0.35) | RORCFKBP1ACYP2C9LMNAALDH1A1 | |
| SCHEMBL2924813 | 1.00 | RORC (0.35) | RORCFKBP1ACYP2C9LMNAALDH1A1 | |
| SCHEMBL2919239 | 0.96 | RORC (0.35) | RORCCYP2C9KMT2A | |
| SCHEMBL2919237 | 0.96 | RORC (0.35) | RORCCYP2C9KMT2A | |
| SCHEMBL2919274 | 0.96 | RORC (0.35) | RORCCYP2C9KMT2A | |
| SCHEMBL2919069 | 0.95 | RORC (0.36) | RORCFKBP1ACYP2C9LMNAALDH1A1 | |
| SCHEMBL2919072 | 0.95 | RORC (0.36) | RORCFKBP1ACYP2C9LMNAALDH1A1 | |
| SCHEMBL2920447 | 0.95 | RORC (0.36) | RORCFKBP1ACYP2C9LMNAALDH1A1 | |
| SCHEMBL2919684 | 0.95 | RORC (0.36) | RORCFKBP1ACYP2C9LMNAALDH1A1 | |
| SCHEMBL2944665 | 0.95 | RORC (0.36) | RORCFKBP1ACYP2C9LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029628-A1 | 2,4,5-Substituted Piperidines as Renin Inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029628-A1 | 2,4,5-Substituted Piperidines as Renin Inhibitors | REN, AGT, AGTR1 | RORC 4757/4885FKBP1A 3930/4885CYP2C9 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.