Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207825 | 0.73 | HSD17B10 (0.33) | HSD17B10MAPTTSHRKMT2AKDM4E | |
| SCHEMBL1654688 | 0.67 | HSD17B10 (1.00) | HSD17B10MAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL8444769 | 0.65 | HSD17B10 (0.35) | HSD17B10MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL6938651 | 0.64 | HSD17B10 (0.47) | HSD17B10MAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL3672729 | 0.63 | KDM4E (0.37) | HSD17B10MAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL10804734 | 0.63 | HPGD (0.41) | HSD17B10MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8819550 | 0.63 | HSD17B10 (0.31) | HSD17B10MAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL4971363 | 0.61 | — | — | |
| SCHEMBL20796 | 0.61 | — | — | |
| SCHEMBL4748477 | 0.61 | ALDH1A1 (0.54) | HSD17B10TSHRALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043218-A2 | TETRATHIOL LIGANDS, METAL COMPLEXES, CONJUGATES, AND KITS, THE USE THEREOF IN NUCLEAR MEDICINE DIAGNOSTICS AND ENDORADIONUCLIDE THERAPY, AND METHOD FOR PRODUCING THE TETRATHIOL LIGANDS AND METAL COMPLEXES | FORSCHUNGSZENTRUM DRESDEN - ROSSENDORF E. V. (DE) | 2010-04-22 | — | — | WO | disclosed |