Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238525 | 0.81 | TPMT (0.35) | HSD17B10KDM4EHPGDMAPTPTPN1 | |
| SCHEMBL3465913 | 0.73 | HSD17B10 (0.50) | HSD17B10KDM4EHPGDCUL4AMAPT | |
| SCHEMBL3672729 | 0.67 | KDM4E (0.37) | HSD17B10KDM4EHPGDCYP1A2MAPT | |
| SCHEMBL11075154 | 0.65 | ALDH1A1 (0.46) | HSD17B10KDM4EHPGDCYP1A2MAPT | |
| SCHEMBL9656750 | 0.64 | KDM4E (0.61) | HSD17B10KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL6938651 | 0.64 | HSD17B10 (0.47) | HSD17B10KDM4EHPGDCUL4ACYP1A2 | |
| SCHEMBL1401584 | 0.64 | RECQL (0.39) | HSD17B10KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL8819550 | 0.63 | HSD17B10 (0.31) | HSD17B10KDM4EHPGDMAPTTSHR | |
| SCHEMBL17972599 | 0.62 | KDM4E (0.35) | HSD17B10KDM4EHPGDCUL4ACYP1A2 | |
| SCHEMBL6836069 | 0.62 | KMT2A (0.54) | HSD17B10KDM4EHPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298133-B1 | Procedure for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | BAYER CHEMICALS AG (DE) | 2005-01-19 | — | — | EP | disclosed |
| EP-1298133-A1 | Procedure for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | BAYER AG (DE) | 2003-04-02 | — | — | EP | disclosed |