Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671086 | 0.82 | KMT2A (0.33) | HSD17B10HPGDKMT2AMEN1CA12 | |
| SCHEMBL10804734 | 0.81 | HPGD (0.41) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL27997449 | 0.80 | LMNA (0.38) | KDM4EHSD17B10HPGDCA2ALDH1A1 | |
| SCHEMBL9409748 | 0.79 | CUL4A (0.37) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL4607918 | 0.79 | KDM4E (0.36) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL14486887 | 0.79 | MAPT (0.37) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9533816 | 0.79 | KDM4E (0.36) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL5240239 | 0.77 | MAPT (0.41) | HPGDKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11335096 | 0.75 | KEAP1 (0.36) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9026030 | 0.75 | KMT2A (0.34) | KDM4EHSD17B10HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599203-B1 | 1,3-SUBSTITUTED CYCLOALKYL DERIVATIVES CONTAINING ACIDIC, MAINLY HETEROCYCLIC GROUPS, CORRESPONDING PRODUCTION METHOD AND USE OF SAID DERIVATIVES AS MEDICAMENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-10-23 | — | — | EP | disclosed |
| EP-1964844-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1967523-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1964845-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1523488-B1 | NOVEL THIOPHENYLGLYCOSIDE DERIVATIVES, METHODS FOR PRODUCTION THEREOF, MEDICAMENTS COMPRISING SAID COMPOUNDS AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-11-12 | — | — | EP | disclosed |
| EP-1967523-A1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | Sanofi-Aventis Deutschland GmbH (DE) | 2008-09-10 | — | — | EP | disclosed |
| EP-1964845-A1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | Sanofi-Aventis Deutschland GmbH (DE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1964844-A1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | Sanofi-Aventis Deutschland GmbH (DE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1523488-A1 | NOVEL THIOPHENYLGLYCOSIDE DERIVATIVES, METHODS FOR PRODUCTION THEREOF, MEDICAMENTS COMPRISING SAID COMPOUNDS AND USE THEREOF | Aventis Pharma Deutschland GmbH (DE) | 2005-04-20 | — | — | EP | disclosed |
| EP-0915868-B1 | CARBANILIDES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-12-08 | — | — | EP | disclosed |
| EP-1443045-A9 | Carbanilide used as pesticide | Bayer CropScience AG (DE) | 2004-10-20 | — | — | EP | disclosed |
| EP-1443045-A1 | Carbanilide used as pesticide | Bayer CropScience AG (DE) | 2004-08-04 | — | — | EP | disclosed |
| WO-2004007517-A1 | NOVEL THIOPHENYLGLYCOSIDE DERIVATIVES, METHODS FOR PRODUCTION THEREOF, MEDICAMENTS COMPRISING SAID COMPOUNDS AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-01-22 | — | — | WO | disclosed |
| EP-0915868-A1 | CARBANILIDES USED AS PESTICIDES | BAYER AG (DE) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003500-A1 | CARBANILIDES USED AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-29 | — | — | WO | disclosed |
| EP-0065295-A1 | Tryptamine derivatives of thienyloxypropanol amines, process for their preparation, pharmaceutical compositions containing them and preparation of the latter | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-24 | — | — | EP | disclosed |