Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.38 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.38 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.38 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39522 | 0.79 | GRIN2D (0.49) | POLBMEN1PGRKMT2AGPBAR1 | |
| SCHEMBL7559741 | 0.77 | MEN1 (0.38) | MEN1PGRKMT2AGPBAR1APLNR | |
| SCHEMBL1982721 | 0.77 | TP53 (0.46) | MEN1KMT2AGPBAR1TSHRALDH1A1 | |
| SCHEMBL7818937 | 0.73 | PTGS2 (0.44) | POLBMEN1PGRKMT2AGPBAR1 | |
| SCHEMBL15200742 | 0.72 | KMT2A (0.43) | POLBMEN1PGRKMT2APTGS2 | |
| SCHEMBL9182341 | 0.72 | KMT2A (0.52) | POLBMEN1PGRKMT2APTGS2 | |
| SCHEMBL6202118 | 0.72 | MEN1 (0.43) | POLBMEN1PGRKMT2ACYP2C9 | |
| SCHEMBL3467180 | 0.70 | MEN1 (0.53) | POLBMEN1PGRKMT2AGPBAR1 | |
| SCHEMBL18751640 | 0.70 | TP53 (0.51) | MEN1KMT2AGPBAR1TSHRALDH1A1 | |
| SCHEMBL852747 | 0.70 | KMT2A (0.55) | POLBMEN1PGRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234485-A1 | STABLE LAQUINIMOD PREPARATIONS | Teva Pharmaceutical Industries Ltd. (IL) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009082471-A1 | STABLE LAQUINIMOD PREPARATIONS | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2009-07-02 | — | — | WO | disclosed |