Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466330 | 1.00 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYP2D6SIGMAR1 | |
| SCHEMBL8296155 | 0.82 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CYP2D6TACR1 | |
| SCHEMBL8300496 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP2D6TACR1 | |
| Hydrochloric Acid SCHEMBL8742517 | 0.79 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CYP2D6TACR1 | |
| SCHEMBL28845080 | 0.78 | SLC6A4 (0.59) | SLC6A2SLC6A4SLC6A3CYP2D6SIGMAR1 | |
| SCHEMBL1981733 | 0.78 | SLC6A4 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL1981732 | 0.78 | SLC6A4 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL3466983 | 0.78 | SLC6A4 (0.76) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL3466065 | 0.78 | SLC6A4 (0.76) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL13345113 | 0.78 | SLC6A4 (0.76) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071575-A1 | QUATERNARY PIPERIDINE DERIVATIVES AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | WO | claimed |
| WO-2010071575-A1 | QUATERNARY PIPERIDINE DERIVATIVES AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | WO | disclosed |