Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 16/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466330 | 0.78 | SLC6A2 (0.63) | SLC6A4SLC6A2SLC6A3CYP2D6SIGMAR1 | |
| SCHEMBL3466336 | 0.78 | SLC6A2 (0.63) | SLC6A4SLC6A2SLC6A3CYP2D6SIGMAR1 | |
| SCHEMBL3517292 | 0.75 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3521434 | 0.75 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8296155 | 0.74 | SLC6A2 (0.60) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL5085593 | 0.74 | SLC6A4 (0.72) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL15043689 | 0.74 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5085612 | 0.74 | SLC6A3 (0.76) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3522145 | 0.73 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9027256 | 0.73 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101394847-B | Cycloalkylamines as monoamine reuptake inhibitors | 塞普拉柯公司 | 2017-05-24 | — | — | CN | claimed |