Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.61 |
| ▸ | EED | O75530 | 3/20 | 0.47 |
| ▸ | TTK | P33981 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.42 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467720 | 0.89 | FYN (0.62) | FYNEEDTTKALDH1A1ZAP70 | |
| SCHEMBL3476687 | 0.85 | EED (0.51) | FYNEEDTTKZAP70KARS1 | |
| SCHEMBL3469327 | 0.83 | EED (0.48) | FYNEEDTTKALDH1A1HTT | |
| SCHEMBL3470178 | 0.82 | TTK (0.67) | FYNTTK | |
| SCHEMBL5396387 | 0.81 | FYN (0.48) | FYNTTK | |
| SCHEMBL3467556 | 0.80 | EED (0.51) | EEDTTKALDH1A1HTTMEN1 | |
| SCHEMBL3469470 | 0.80 | EED (0.51) | FYNEEDTTKALDH1A1MAPT | |
| SCHEMBL3466394 | 0.80 | EED (0.51) | EEDTTKZAP70KARS1 | |
| SCHEMBL12409245 | 0.79 | TTK (0.49) | FYNTTKZAP70 | |
| SCHEMBL12409314 | 0.79 | MAPK1 (0.50) | FYNEEDTTKALDH1A1ZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |