SCHEMBL3470178

SCHEMBL3470178

CC(=O)c1cccc(-c2cnc3c(NCC(C)C)nccn23)c1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TTK P33981 17/20 0.67
FYN P06241 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3470453 0.88 TTK (0.64) TTKFYN
SCHEMBL3466151 0.85 TTK (0.62) TTK
SCHEMBL5396387 0.85 FYN (0.48) TTKFYN
SCHEMBL3466367 0.82 FYN (0.61) TTKFYN
SCHEMBL9938190 0.81 TTK (0.82) TTK
SCHEMBL12409319 0.81 TTK (0.47) TTKFYN
SCHEMBL12409245 0.80 TTK (0.49) TTKFYN
SCHEMBL3467927 0.78 TTK (0.74) TTK
SCHEMBL3469482 0.76 TTK (0.71) TTK
SCHEMBL5411929 0.76 IKBKB (0.49) TTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010069684-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-06-24 WO claimed
WO-2010069684-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-06-24 WO disclosed