Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 11/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | EED | O75530 | 2/20 | 0.46 |
| ▸ | TTK | P33981 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.43 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466367 | 0.89 | FYN (0.61) | FYNMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL3476687 | 0.84 | EED (0.51) | FYNEEDTTKZAP70KARS1 | |
| SCHEMBL3466505 | 0.83 | FYN (0.58) | FYNTTKBRAF | |
| SCHEMBL3470453 | 0.82 | TTK (0.64) | FYNTTKBRAF | |
| SCHEMBL5416134 | 0.82 | FYN (0.54) | FYNTTKBRAF | |
| SCHEMBL3469327 | 0.81 | EED (0.48) | FYNMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3469619 | 0.81 | TTK (0.59) | FYNTTK | |
| SCHEMBL3469970 | 0.80 | BRAF (0.57) | FYNMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12409290 | 0.80 | TTK (0.46) | FYNTTKZAP70BRAF | |
| SCHEMBL3466056 | 0.80 | TTK (0.57) | FYNSMN1; SMN2TTKTP53BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |