Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646553 | 0.92 | MMP12 (0.56) | MMP12MMP13MMEEGLN1FFAR1 | |
| SCHEMBL7457241 | 0.86 | FAAH (0.48) | MMP12MMP13MMEEGLN1MGLL | |
| SCHEMBL31225965 | 0.84 | MMP12 (0.52) | MMP12MMP13MMEEGLN1XDH | |
| SCHEMBL1337450 | 0.82 | CYP11B1 (0.54) | FFAR1 | |
| SCHEMBL29165966 | 0.82 | FFAR1 (0.48) | FFAR1FFAR4FAAH | |
| SCHEMBL1309936 | 0.81 | MME (0.46) | MMEFFAR1MGLL | |
| SCHEMBL12646561 | 0.80 | FFAR1 (0.50) | MMP12MMP13FFAR1FFAR4 | |
| SCHEMBL19608719 | 0.79 | TSHR (0.58) | MMP12MMP13MMEFFAR1FAAH | |
| SCHEMBL12646477 | 0.79 | FFAR1 (0.70) | MMP12MMP13MMEFFAR1FFAR4 | |
| SCHEMBL3628694 | 0.78 | CYP11B1 (0.56) | MMP12MMP13EGLN1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |