Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 3/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466551 | 1.00 | FFAR1 (0.51) | FFAR1FFAR4GSK3BBACE1MMP12 | |
| SCHEMBL1857515 | 0.89 | GSK3B (0.50) | FFAR1FFAR4GSK3BBACE1MMP12 | |
| SCHEMBL1857512 | 0.89 | GSK3B (0.50) | FFAR1FFAR4GSK3BBACE1MMP12 | |
| SCHEMBL1857645 | 0.87 | GRIK1 (0.60) | GRIK1GRIK2 | |
| SCHEMBL1857647 | 0.87 | GRIK1 (0.60) | GRIK1GRIK2 | |
| SCHEMBL28224291 | 0.81 | FFAR1 (0.64) | FFAR1FFAR4MMP12PPARGPPARA | |
| SCHEMBL28860722 | 0.81 | FFAR1 (0.64) | FFAR1FFAR4MMP12PPARGPPARA | |
| SCHEMBL1856449 | 0.80 | LTA4H (0.60) | FFAR1FFAR4MMP12PPARGPPARA | |
| SCHEMBL1857513 | 0.79 | MAOB (0.50) | FFAR1FFAR4MMP12PPARGPPARA | |
| SCHEMBL27439147 | 0.79 | LTA4H (0.58) | FFAR1FFAR4MMP12PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |