SCHEMBL3466564

SCHEMBL3466564

Cc1ccc(OC(C)Oc2ccc(C)cc2C)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
TSHR P16473 2/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
PABPC1 P11940 1/20 0.40
EIF4H Q15056 1/20 0.40
HTR1A P08908 1/20 0.40
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 6/20 0.39
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8280908 0.86 FFAR4 (0.43) ACHETSHRHTR2AHTR2CHTR2B
SCHEMBL5283288 0.86 ACHE (0.44) ACHETSHRHTR2AHTR2CHTR2B
SCHEMBL10359314 0.83 HTR2B (0.42) ACHETSHRHTR2AHTR2CHTR2B
SCHEMBL17816443 0.83 ACHE (0.40) ACHETSHRHTR2AHTR2CHTR2B
SCHEMBL9032996 0.83 ACHE (0.40) ACHETSHRHTR2AHTR2CHTR2B
SCHEMBL5286553 0.82 ACHE (0.43) ACHETSHRHTR2BTDP1ALDH1A1
SCHEMBL24243444 0.81 HTR1A (0.40) ACHETSHRHTR2AHTR2CHTR2B
SCHEMBL6876872 0.80 ALDH1A1 (0.50) ACHETP53TDP1L3MBTL1ALDH1A1
SCHEMBL24521488 0.80 ACHE (0.41) ACHETSHRHTR2AHTR2CHTR2B
SCHEMBL10188117 0.79 SMN1; SMN2 (0.41) ACHEHTR1ATDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010075544-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. (US) 2010-07-01 WO claimed
WO-2010075544-A1 NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. (US) 2010-07-01 WO disclosed
WO-2009097433-A1 NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. (US) 2009-08-06 WO disclosed
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed