Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466713 | 0.85 | MEN1 (0.62) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL11873110 | 0.76 | TAS1R3 (0.57) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL5471126 | 0.74 | RAB9A (0.65) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL20548599 | 0.74 | MEN1 (0.55) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL3467505 | 0.72 | KMT2A (0.51) | SMN1; SMN2RAB9ANPC1MAPTMCL1 | |
| SCHEMBL3729161 | 0.71 | KMT2A (0.47) | ALDH1A1SMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL3467090 | 0.71 | MEN1 (0.68) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL5441846 | 0.70 | KMT2A (0.71) | ALDH1A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL5445021 | 0.70 | KMT2A (0.60) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL3731624 | 0.69 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |