Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1116718 | 0.91 | CA12 (0.31) | CA12CA1CA9HTR1BKDM5A | |
| SCHEMBL16714875 | 0.89 | KDM5A (0.33) | CA12CA1CA9HTR1BKDM5A | |
| SCHEMBL1138386 | 0.83 | DNM1 (0.39) | CA12CA1CA9KDM5ADRD3 | |
| SCHEMBL16714782 | 0.80 | MAOA (0.32) | — | |
| SCHEMBL914852 | 0.78 | MEN1 (0.32) | — | |
| SCHEMBL274371 | 0.75 | — | — | |
| SCHEMBL23282519 | 0.74 | ALDH1A1 (0.34) | — | |
| SCHEMBL3904839 | 0.74 | TSHR (0.46) | CA12CA1CA9KDM5AMAPT | |
| SCHEMBL27566038 | 0.74 | TSHR (0.46) | CA12CA1CA9KDM5AMAPT | |
| SCHEMBL896 | 0.74 | TSHR (0.46) | CA12CA1CA9KDM5AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816009-B2 | Organosilyl functionalized particles and the production thereof | WACKER CHEMIE AG (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20060020097-A1 | Organosilyl functionalized particles and the production thereof | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2006-01-26 | — | — | US | disclosed |