Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | TTK | P33981 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401154 | 0.81 | FLT3 (0.54) | FLT3TTKIDO1 | |
| SCHEMBL3466360 | 0.77 | TTK (0.53) | FLT3TTKALDH1A1LMNA | |
| SCHEMBL3470355 | 0.76 | CYP1A2 (0.53) | FLT3TTKALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3466464 | 0.76 | TTK (0.48) | FLT3TTK | |
| SCHEMBL3467192 | 0.76 | TTK (0.56) | FLT3TTKALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8240004 | 0.76 | FLT3 (0.40) | FLT3TTKCYP3A4LMNAUTS2R | |
| SCHEMBL3470277 | 0.75 | FYN (0.54) | FLT3TTK | |
| SCHEMBL8246959 | 0.74 | AURKA (0.54) | FLT3TTK | |
| SCHEMBL3467735 | 0.72 | PGK1 (0.47) | FLT3TTKALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5401149 | 0.71 | CCNE2 (0.41) | FLT3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |