Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466693 | 0.87 | CA1 (0.40) | CA2ALDH1A1 | |
| SCHEMBL3467086 | 0.85 | MEN1 (0.39) | CTSKCTSBCA2CTSLCTSS | |
| SCHEMBL3466268 | 0.85 | CTSL (0.40) | CTSKCTSBCTSLCTSSALDH1A1 | |
| SCHEMBL27821616 | 0.85 | CTSL (0.40) | CTSKCTSBCTSLCTSSALDH1A1 | |
| SCHEMBL3466972 | 0.82 | CA9 (0.39) | MMP1MMP2MMP9MMP13CA2 | |
| SCHEMBL3466897 | 0.74 | KMT2A (0.47) | MMP1MMP2MMP9MMP13CA2 | |
| SCHEMBL18853809 | 0.73 | CA2 (0.45) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL13296183 | 0.71 | PLCG1 (0.42) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL7694180 | 0.71 | PLCG1 (0.42) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL28928743 | 0.71 | GLA (0.41) | CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070593-A2 | MALONATE ESTERS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070593-A2 | MALONATE ESTERS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2010-06-24 | — | — | WO | disclosed |