Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467086 | 0.87 | MEN1 (0.39) | CA1CA2CA4CA9MEN1 | |
| SCHEMBL3466941 | 0.87 | CTSK (0.40) | CA2ALDH1A1 | |
| SCHEMBL3466268 | 0.86 | CTSL (0.40) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL27821616 | 0.86 | CTSL (0.40) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL28928743 | 0.84 | GLA (0.41) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL3935202 | 0.84 | GLA (0.41) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL3466972 | 0.83 | CA9 (0.39) | CA1CA2CA4CA9ALDH1A1 | |
| SCHEMBL27821620 | 0.82 | CA12 (0.44) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL3052582 | 0.81 | GLA (0.42) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL18718195 | 0.80 | CA2 (0.46) | CA1CA2CA4CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070593-A2 | MALONATE ESTERS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070593-A2 | MALONATE ESTERS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2010-06-24 | — | — | WO | disclosed |