Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467614 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3468399 | 0.75 | RAB9A (0.58) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3476631 | 0.74 | KMT2A (0.45) | RAB9ANPC1ALDH1A1HPGDKMT2A | |
| SCHEMBL11679404 | 0.74 | PTGS2 (0.61) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3468757 | 0.74 | ALDH1A1 (0.58) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3467903 | 0.72 | KMT2A (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL14966349 | 0.72 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3472921 | 0.71 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3466740 | 0.70 | NPC1 (0.52) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL14970882 | 0.70 | KMT2A (0.72) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |