Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | BLM | P54132 | 7/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.64 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.64 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | WRN | Q14191 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11875081 | 0.84 | BLM (0.80) | RAB9ANPC1MAPTBLMHTT | |
| SCHEMBL3467256 | 0.81 | MEN1 (0.74) | RAB9ANPC1MAPTBLMHTT | |
| SCHEMBL8561964 | 0.79 | HTT (0.75) | RAB9ANPC1MAPTBLMHTT | |
| SCHEMBL3467221 | 0.79 | MAPT (0.77) | RAB9AMAPTBLMHTTMEN1 | |
| SCHEMBL3467177 | 0.79 | RAB9A (0.64) | RAB9ANPC1MAPTBLMHTT | |
| SCHEMBL8559872 | 0.78 | HTT (0.73) | RAB9ANPC1MAPTBLMHTT | |
| SCHEMBL24232990 | 0.78 | NPC1 (0.67) | RAB9ANPC1MAPTBLMHTT | |
| SCHEMBL8569537 | 0.77 | HTT (1.00) | RAB9ANPC1MAPTBLMHTT | |
| SCHEMBL2030731 | 0.77 | HPN (1.00) | RAB9ANPC1BLMHTTMEN1 | |
| SCHEMBL12642191 | 0.77 | BLM (0.78) | RAB9ANPC1BLMHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |