Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.59 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467894 | 0.84 | MEN1 (0.62) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467256 | 0.82 | MEN1 (0.74) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467864 | 0.79 | MEN1 (0.59) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467385 | 0.79 | RAB9A (0.69) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467362 | 0.77 | CA1 (0.54) | RAB9ASMN1; SMN2HTTNPC1CA1 | |
| SCHEMBL14970871 | 0.76 | RAB9A (0.74) | RAB9ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL8565680 | 0.76 | MAPT (0.60) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467231 | 0.75 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467221 | 0.74 | MAPT (0.77) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7478008 | 0.73 | MAPT (0.63) | RAB9ASMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |