Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467260 | 0.89 | MMP2 (0.60) | FDFT1MMP2MMP3GRIK1MME | |
| SCHEMBL1860684 | 0.89 | LTA4H (0.53) | FDFT1MMP2MMP3GRIK1PLAAT3 | |
| SCHEMBL1861903 | 0.87 | GRIK1 (0.59) | FDFT1MMP2MMP3GRIK1MME | |
| SCHEMBL3466524 | 0.87 | FDFT1 (0.51) | FDFT1MMP2MMP3PLAAT3PLAAT5 | |
| SCHEMBL7929539 | 0.86 | MMP2 (0.48) | FDFT1MMP2MMP3PPARAPPARD | |
| SCHEMBL7924101 | 0.85 | GRIK1 (0.54) | FDFT1MMP2MMP3GRIK1MME | |
| SCHEMBL8041638 | 0.84 | GRIK1 (0.56) | FDFT1MMP2MMP3GRIK1MME | |
| SCHEMBL3468514 | 0.84 | SLC13A5 (0.53) | MMP2MMP3GRIK1MMEPPARA | |
| SCHEMBL1860416 | 0.83 | GRIK1 (0.68) | MMP2MMP3GRIK1PPARAPPARG | |
| SCHEMBL7922577 | 0.82 | PPARG (0.56) | FDFT1MMP2MMP3GRIK1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |