SCHEMBL3467655

SCHEMBL3467655

CCCCCCCCCC(F)C(F)C(F)CC

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
OPRM1 P35372 1/20 0.37
GPR84 Q9NQS5 3/20 0.35
FDPS P14324 3/20 0.35
SPHK1 Q9NYA1 1/20 0.35
FFAR1 O14842 1/20 0.35
CES2 O00748 1/20 0.35
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11967115 0.84 MAPT (0.42) MAPTLMNADNM1TSHRTHRB
SCHEMBL11967114 0.84 MAPT (0.42) MAPTLMNADNM1TSHRTHRB
SCHEMBL25600749 0.76 MAPT (0.43) MAPTLMNADNM1TSHRTHRB
SCHEMBL27487568 0.76 GPR84 (0.56) MAPTTSHRGPR84FFAR1LCK
SCHEMBL24920047 0.75 MAPT (0.46) MAPTLMNADNM1TSHRTHRB
SCHEMBL20411871 0.75 MAPT (0.46) MAPTLMNADNM1TSHRTHRB
SCHEMBL22756700 0.75 OPRM1 (0.46) MAPTLMNADNM1TSHRTHRB
SCHEMBL27690588 0.74 ALDH1A1 (0.40) MAPTLMNADNM1TSHRFDPS
SCHEMBL20076558 0.73 MAPT (0.45) MAPTLMNADNM1TSHRTHRB
SCHEMBL28779372 0.73 MAPT (0.45) MAPTLMNADNM1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120167825-A1 HALOGEN ASSISTED PHYSICAL VAPOR TRANSPORT METHOD FOR SILICON CARBIDE GROWTH MUELLER STEPHAN G (US) 2012-07-05 US disclosed
US-8163086-B2 Halogen assisted physical vapor transport method for silicon carbide growth CREE, INC. (US) 2012-04-24 US disclosed
US-20090056619-A1 Halogen Assisted Physical Vapor Transport Method for Silicon Carbide Growth U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2009-03-05 US disclosed