Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798396 | 0.90 | ALDH1A1 (0.44) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL30780970 | 0.90 | ALDH1A1 (0.44) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL30127220 | 0.84 | ALDH1A1 (0.47) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL193774 | 0.84 | ALDH1A1 (0.47) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL524891 | 0.78 | MAPT (0.47) | ALDH1A1MAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL29503510 | 0.78 | MAPT (0.47) | ALDH1A1MAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL310330 | 0.77 | ALDH1A1 (0.45) | TDP1ALDH1A1MAPTCYP3A4LMNA | |
| SCHEMBL221284 | 0.77 | ALDH1A1 (0.61) | TDP1ATMALDH1A1HSPB1MAPT | |
| SCHEMBL29588929 | 0.77 | ALDH1A1 (0.61) | TDP1ATMALDH1A1HSPB1MAPT | |
| SCHEMBL1766175 | 0.77 | ALDH1A1 (0.58) | TDP1ATMALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077915-A1 | NOVEL COMPOUNDS USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-08 | — | — | WO | disclosed |