Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798396 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TDP1HIF1AMAPTCYP3A4 | |
| SCHEMBL193774 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1HIF1AMAPTCYP3A4 | |
| SCHEMBL30127220 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1HIF1AMAPTCYP3A4 | |
| SCHEMBL3467728 | 0.90 | TDP1 (0.49) | ALDH1A1TDP1HIF1AMAPTCYP3A4 | |
| SCHEMBL310330 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1MAPTCYP3A4KDM4E | |
| SCHEMBL31377991 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1HIF1AMAPTCYP3A4 | |
| SCHEMBL1766175 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1HIF1AMAPTCYP3A4 | |
| SCHEMBL4279356 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TDP1HIF1AMAPTCYP3A4 | |
| SCHEMBL11661312 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TDP1MAPTCYP3A4KDM4E | |
| SCHEMBL2874199 | 0.84 | LMNA (0.50) | ALDH1A1TDP1MAPTCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |