SCHEMBL346789

SCHEMBL346789

CC(C(=O)O)c1ccc(CBr)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 13/20 0.67
PTGS1 P23219 12/20 0.67
AKR1C3 P42330 3/20 0.67
LMNA P02545 2/20 0.67
CYP2C9 P11712 2/20 0.67
CXCR1 P25024 2/20 0.67
CXCR2 P25025 2/20 0.67
AKR1C2 P52895 2/20 0.67
ALB P02768 1/20 0.67
ESR1 P03372 1/20 0.67
ALOX5 P09917 1/20 0.67
RARB P10826 1/20 0.67
ADRB3 P13945 1/20 0.67
NFKB1 P19838 1/20 0.67
HTR2A P28223 1/20 0.67
NR1I3 Q14994 1/20 0.67
SLC22A6 Q4U2R8 1/20 0.67
CXCL8 P10145 1/20 0.67
TSHR P16473 1/20 0.67
BLM P54132 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28892665 0.91 PTGS2 (0.57) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL18905163 0.88 PTGS1 (0.52) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL27791170 0.86 PTGS1 (0.48) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL27730616 0.85 PTGS2 (0.62) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL59197 0.82 PTGS2 (0.74) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL348792 0.82 FAAH (0.46) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL29107974 0.82 EPHX1 (0.68) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL2883757 0.82 PTGS2 (0.69) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL1512673 0.82 PTGS2 (0.69) PTGS2PTGS1AKR1C3LMNACYP2C9
SCHEMBL29390746 0.82 PTGS2 (0.69) PTGS2PTGS1AKR1C3LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137643-A Composite material, preparation method thereof, photoelectric device and display device 广东聚华新型显示研究院 2025-06-13 CN claimed
CN-118515552-A Improved industrial production process of 2- (4-bromomethylphenyl) propionic acid 程冬冬 2024-08-20 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-114702608-B Esterase response polymer and application thereof 浙江大学 2024-01-26 CN claimed
CN-116354814-A Processing technology for improving purity of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-06-30 CN claimed
CN-115710173-A Preparation method of p-bromomethylphenyl propionic acid 贵州天豪民族药业有限公司 2023-02-24 CN claimed
CN-114702608-A Esterase response polymer and application thereof 浙江大学 2022-07-05 CN claimed
CN-107573230-B Synthetic method of p-bromomethyl phenylpropionic acid 重庆沃肯精细化工有限公司 2021-09-14 CN claimed
CN-113149826-A Preparation process of pelubiprofen 台州市源众药业有限公司 2021-07-23 CN claimed
CN-108586233-B Method for synthesizing 2- (4' -bromomethylphenyl) propionate 湖北迅达药业股份有限公司 2021-05-18 CN claimed
CN-109180470-B Preparation of 2- (4-bromomethylphenyl) propionic acid by liquid phase circulation method 浙江大学 2021-02-02 CN claimed
CN-107473960-B Method and device for preparing 2- (4-bromomethylphenyl) propionic acid in pipeline manner 浙江工业大学 2021-01-05 CN claimed
CN-109180464-B Preparation of 2- (4-bromomethylphenyl) propionic acid by gas phase circulation method 浙江大学 2020-08-07 CN claimed
CN-109776300-B Synthetic method of loxoprofen sodium 浙江大学 2020-08-07 CN claimed
CN-110790662-A Production method of 2- (4-bromomethylphenyl) propionic acid 怀化泰通新材料科技有限公司 2020-02-14 CN claimed
EP-0889020-B1 A process for the production of benzene derivatives KOLON INC (KR) 2001-11-14 EP claimed
US-6013832-A Process for the production of benzene derivatives KOLON INDUSTRIES, INC. (KR) 2000-01-11 US claimed
EP-0889020-A1 A process for the production of benzene derivatives Kolon Industries, Inc. (KR) 1999-01-07 EP claimed
CN-120137643-A Composite material, preparation method thereof, photoelectric device and display device 广东聚华新型显示研究院 2025-06-13 CN disclosed
EP-0889020-A1 A process for the production of benzene derivatives Kolon Industries, Inc. (KR) 1999-01-07 EP disclosed