Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 3/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467495 | 0.74 | ALDH1A1 (0.49) | GLSSCN1ASCN8AMEN1MAPT | |
| SCHEMBL3467354 | 0.73 | ALDH1A1 (0.61) | SCN1ASCN8AMEN1MAPTKMT2A | |
| SCHEMBL17610198 | 0.64 | MEN1 (0.42) | NPSR1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL10913301 | 0.63 | MEP1B (0.50) | KCNJ5KCNJ3MEP1BDAONPSR1 | |
| SCHEMBL1776057 | 0.63 | MEP1B (0.54) | KCNJ5KCNJ3MEP1BDAONPSR1 | |
| SCHEMBL1776056 | 0.63 | MEP1B (0.54) | KCNJ5KCNJ3MEP1BDAONPSR1 | |
| SCHEMBL2376734 | 0.63 | MEP1B (0.48) | KCNJ5KCNJ3MEP1BDAONPSR1 | |
| SCHEMBL2376739 | 0.63 | MEP1B (0.48) | MEP1BDAOMRGPRX4 | |
| SCHEMBL15042279 | 0.62 | MEP1B (0.54) | MEP1BDAOMRGPRX4 | |
| SCHEMBL14378247 | 0.62 | MEP1B (0.47) | MEP1BDAOROCK2KMT2AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |