SCHEMBL346866

SCHEMBL346866

C=C(C)C(=O)OCCCCCOP(=O)(O)O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
LPAR3 Q9UBY5 8/20 0.53
LPAR2 Q9HBW0 6/20 0.53
LPAR1 Q92633 4/20 0.53
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
THRB P10828 1/20 0.46
ALDH1A1 P00352 1/20 0.40
BTN3A1 O00481 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30617843 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL1653308 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL15795 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL15166 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL345787 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL345385 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL346923 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL1651991 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL345903 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB
SCHEMBL345072 1.00 TSHR (0.62) TSHRLPAR3LPAR2LPAR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250900-B Water-based epoxy graphene low-zinc antirust primer 明光科迪新材料有限公司 2020-09-04 CN claimed
CN-108165069-B High-content aqueous graphene dispersion liquid and preparation method thereof 明光科迪新材料有限公司 2020-09-01 CN claimed
EP-2492289-B1 POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL KURARAY NORITAKE DENTAL INC (JP) 2020-03-18 EP claimed
US-9333148-B2 Polymerizable composition and dental material KURARAY NORITAKE DENTAL INC. (JP) 2016-05-10 US claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
CN-102802590-A Epoxy-containing compositions curable by multiple polymerization mechanisms PENTRON CLINICAL TECHNOLOGIES LLC 2012-11-28 CN claimed
US-6984673-B2 Dental cement composition KURARAY CO., LTD. (JP) 2006-01-10 US claimed
EP-0468077-A1 Dental adhesive MITSUBISHI RAYON CO., LTD. (JP) 1992-01-29 EP claimed
JP-58021687-A None JP disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
US-20240199494-A1 ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF Kuraray Noritake Dental lnc. (JP) 2024-06-20 US disclosed
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT SHOFU INC. (JP) 2024-05-30 US disclosed
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME KURARAY NORITAKE DENTAL INC. (JP) 2024-05-23 US disclosed
US-4650847-A DENTISTRY KURARAY CO., LTD. (JP) 1987-03-17 US disclosed
US-4612384-A Phosphate monoester adhesive composition KURARAY CO., LTD. (JP) 1986-09-16 US disclosed
EP-0074708-B1 ADHESIVE COMPOSITION KURARAY CO., LTD. (JP) 1986-02-19 EP disclosed
US-4539382-A ACRYLIC PHOSPHORIC ACID DERIVATIVE KURARAY CO., LTD. (JP) 1985-09-03 US disclosed
EP-0074708-A2 Adhesive composition KURARAY CO., LTD. (JP) 1983-03-23 EP disclosed
JP-S5821687-A (METH)ACRYLOYLOXYALKYL DIHYDROGENPHOSPHATE AND ITS PREPARATION KURARAY CO LTD 1983-02-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL TSHR 4710/4885LPAR3 2934/4885LPAR2 3391/4885
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME MSL1, ITGA1, ASH2L TSHR 4172/4885LPAR3 3932/4885LPAR2 4249/4885
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT GRIK1, GRIN2B, GRIK2 TSHR 2655/4885LPAR3 4577/4885LPAR2 4592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.